The Nonnatus team oversee the care of a man living inside an iron lung.

Cromwell brings Anne of Cleves to England to be Henry’s new wife.

The sisters welcome a new postulant, Sister Catherine, to Nonnatus House.

The birth of a prince comes at a terrible price and Cromwell must help the King remarry.

Rosalind delivers a baby with a suspicious spinal lesion. A sudden gas explosion shocks all.

Rebels in the North demand Cromwell’s head and a return to the old Catholic ways. With King Henry VIII beginning to contemplate his chief adviser’s failings, Cromwell withdraws from court and receives unexpected news from across the sea.

Trixie cares for a single mother recently discharged from a psychiatric hospital.

A secret marriage brings scandal to court, giving Cromwell the opportunity to bring his adversary Norfolk down for good.

Protests on the Isle of Dogs cause chaos for the Nonnatus team, while an apparent immaculate conception concerns the midwives. Sister Julienne and Trixie plan to fight back the Board of Health’s disapproval of the way Nonnatus House operates.

As Henry and Jane enjoy wedded bliss, Cromwell risks all to save Princess Mary from her father’s ire.